Causes and Risk Factors of Kidney Stone
Several factors increase the risk for developing kidney stones, including inadequate fluid intake and dehydration, reduced urinary volume, certain chemical levels in the urine that are too high (e.g., calcium, oxalate, uric acid) or too low (magnesium, citrate), and several medical conditions such as reflux, medullary sponge kidney, renal tubular acidosis and urinary tract infections (UTIs). Anything that blocks or reduces the flow of urine (e.g., urinary obstruction, genetic abnormalities) also increases the risk.
Chemical risk factors include high levels of the following in the urine:
Low levels of these inhibitors can contribute to the formation of kidney stones. Of these, citrate is the most important.
The following medical conditions are also risk factors for kidney stone disease:
Diet plays an important role in the development of kidney stones, especially in patients who are predisposed to the condition. A diet high in sodium, fats, meat, and low in fiber, vegetable protein, and unrefined carbohydrates increases the risk for renal stone disease. Recurrent kidney stones may form in patients who are sensitive to the chemical by products of animal protein and who consume large amounts of meat.
Oxalate is found in, Red meat (beef, pork, mutton), vegetables (e.g., greens, spinach,), nuts, chocolate, coffee and strong tea. Stone formers should limit their intake of these items, which contain a moderate amount of oxalate.